PermeaDerm, Inc.

Wound Dressing Comparisons

Material Indication Contraindication Porosity Storage Requirement
Apligraf®1 Living, bi-layered skin substitute Non-infected partial and full-thickness venous skin ulcers, diabetic foot ulcers - Clinically infected wounds
- Patients with known allergies to bovine collagen or hypersensitivity to the shipping medium
May be perforated to allow for drainage Keep sealed bag at 68°F-73°F (20°C-23°C) until use
Biobrane® and Biobrane®-L2 Silicon bonded to nylon fabric Burn wounds, donor sites, meshed autografts None listed None listed Room temperature
Dermagraft®3 Cryopreserved human fibroblasts Diabetic foot ulcers - Ulcers that have signs of clinical infection or with sinus tracts.
- Patients with hypersensitivity to bovine products
None listed Must be stored continuously @ -75°C ± 10°
E-Z Derm®4 Porcine xenograft Partial-thickness skin loss, donor sites, skin ulcerations, abrasions None listed Available as perforated product 18 months at room temperature
Oasis® Ultra5 Tri-layer matrix; porcine source Management of wounds (see reference for list) - Patients with sensitivity to porcine material
- Third degree burn wounds
Sheet may be cut to allow drainage Room temperature
PermeaDerm B, PermeaDerm C Slitted silicone and nylon fabric with bio-coating Acute and chronic wounds Hypersensitive to product components Variable; determined by surgeon Room temperature
  6. PermeaDerm product is pre-clinical and not yet FDA approved for use; data on file

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