PermeaDerm, Inc.

Wound Dressing Comparisons

Material Indication Contraindication Porosity Storage Requirement
Apligraf®1 Living, bi-layered skin substitute Non-infected partial and full-thickness venous skin ulcers, diabetic foot ulcers - Clinically infected wounds
- Patients with known allergies to bovine collagen or hypersensitivity to the shipping medium
May be perforated to allow for drainage Keep sealed bag at 68°F-73°F (20°C-23°C) until use
Biobrane® and Biobrane®-L2 Silicon bonded to nylon fabric Burn wounds, donor sites, meshed autografts None listed None listed Room temperature
Dermagraft®3 Cryopreserved human fibroblasts Diabetic foot ulcers - Ulcers that have signs of clinical infection or with sinus tracts.
- Patients with hypersensitivity to bovine products
None listed Must be stored continuously @ -75°C ± 10°
E-Z Derm®4 Porcine xenograft Partial-thickness skin loss, donor sites, skin ulcerations, abrasions None listed Available as perforated product 18 months at room temperature
Oasis® Ultra5 Tri-layer matrix; porcine source Management of wounds (see reference for list) - Patients with sensitivity to porcine material
- Third degree burn wounds
Sheet may be cut to allow drainage Room temperature
PermeaDerm B, PermeaDerm C Slitted silicone and nylon fabric with bio-coating Acute and chronic wounds Hypersensitive to product components Variable; determined by surgeon Room temperature
  1. http://www.apligraf.com/professional/pdf/prescribing_information.pdf
  2. http://www.udllabs.com/burn_care/biobrane.aspx
  3. http://www.dermagraft.com/wp-content/uploads/sites/1/Dermagraft_Directions_for_Use.pdf
  4. http://www.molnlycke.com/advanced-wound-care-systems/skin-grafting-systems/ez-derm/
  5. http://www.oasiswoundmatrix.com/sites/default/files/resources/oasis_ou_instructions_for_use.pdf
  6. PermeaDerm product is pre-clinical and not yet FDA approved for use; data on file

For more information, please contact us.